|
KMID : 0614620090540050309
|
|
Korean Journal of Gastroenterology
2009 Volume.54 No. 5 p.309 ~ p.317
|
|
|
Guidelines of Prevention and Treatment for NSAID-related Peptic Ulcers
|
|
Lee Jun-Haeng
Lee Yong-Chan
Jeon Seong-Woo
Kim Jeong-Wook
Lee Sang-Woo
Korean Association of Gastroenterology
|
|
|
Abstract
|
|
|
|
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used medications in Korea. Gastrointestinal toxicity, including peptic ulcer, is a common adverse effect of NSAIDs. Risk factors for NSAID-related peptic ulcer include a previous history of peptic ulcer, advanced age, high dose, concomitant use of corticosteroids, anticoagulants, other NSAIDs including low-dose aspirin. Preventive measure(s), such as COX-2 inhibitor, proton pump inhibitor or misoprostrol, should be done for patients requiring NSAID therapy who have high-risk factor(s) for peptic ulcer. Low dose aspirin also increases the risk of peptic ulcer, so preventive measure(s) should be done for high-risk patients. The eradication of Helicobacter pylori is recommended for high-risk NSAID-users. Treatment strategies for peptic ulcers in NSAID users are mostly the same for peptic ulcers in NSAID non-users.
|
|
|
KEYWORD
|
|
|
Non-steroidal anti-inflammatory drug, Peptic ulcer, Prevention, Guideline
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|
|